Quantitative suspension test for evaluation of virucidal activity in the medical area (Phase 2 Step1). Against COVID-19 Surrogate (Feline Coronavirus.)
Result:
5 Minute Contact Time: 99.9% Reduction
1 Hour Contact Time: 99.99% Reduction
The Patent:
Zn2+ inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. te Velthuis A.J.W., van den Worml S.H.E., Sims A.C., Baric R.S., Snijder E.J., van Hemert M.J. (2010) https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1001176
Antiviral Activity of the Zinc Ionophores Pyrithione and Hinokitiol against Picornavirus Infections. Journal of virology. Krenn, B & Gaudernak, E & Holzer, Barbara & Lanke, Kjerstin & Kuppeveld, F. & Seipelt,Joachim(2008). https://www.researchgate.net/publication/23385148_Antiviral_Activity_of_the_Zinc_Ionophores_Pyrithione_and_Hinokitiol_against_Picornavirus_Infections
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https://wwwnc.cdc.gov/eid/article/10/7/03-1113_article
High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. Xu, H., Zhong, L., Deng, J. et al. (2020)
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