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Quantitative suspension test for evaluation of virucidal activity in the medical area (Phase 2 Step1). Against COVID-19 Surrogate (Feline Coronavirus.)

Natural cosmetics

Result:

5 Minute Contact Time: 99.9% Reduction 

1 Hour Contact Time: 99.99% Reduction

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The Patent:

Zn2+ inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. te Velthuis A.J.W., van den Worml S.H.E., Sims A.C., Baric R.S., Snijder E.J., van Hemert M.J. (2010)  https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1001176

Antiviral Activity of the Zinc Ionophores Pyrithione and Hinokitiol against Picornavirus Infections. Journal of virology. Krenn, B & Gaudernak, E & Holzer, Barbara & Lanke, Kjerstin & Kuppeveld, F. & Seipelt,Joachim(2008).  https://www.researchgate.net/publication/23385148_Antiviral_Activity_of_the_Zinc_Ionophores_Pyrithione_and_Hinokitiol_against_Picornavirus_Infections

Detection of SARS-associated coronavirus in throat wash and saliva in early diagnosis. 

Wang, Wei-Kung & Chen, S.Y. & Liu, I.J.. (2004).

https://wwwnc.cdc.gov/eid/article/10/7/03-1113_article

High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. Xu, H., Zhong, L., Deng, J. et al. (2020) 

https://www.nature.com/articles/s41368-020-0074-x?fbclid=IwAR16DWwm90H9wGnzbzjrXu188Jfiv7uz5RdDf-e0ptYNfA8kadCAh-HBxxQ#citeas​

“Antiviral Medication.” - ES2236012T Dong, Liang, Steven Espinal, Patrick Wong, and Paul Magruder. 2007. LINK TO PATENT

 “Antiviral Agent and Throat Candy, Gargle, and Mouthwash Using the Same.” - JP2019077617 Fukui, Atsuko and Takuya Nakatsubo. 2019LINK TO PATENT

“Antibacterial and Antifungal Activity Method, Therapeutic Method of Infectious Diseases and Preserving Method of Cosmetics.” - US5696169A Otsu, Yoshiro, Yaeno Arima, and Yoriko Nakai. 1997. LINK TO PATENT

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